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The primary artificial transposon designed for use in vertebrate (including human) cells, the Sleeping Magnificence transposon system, is a Tc1/mariner-like transposon. Its useless ("fossil") versions are spread widely within the salmonid genome and a functional version was engineered by evaluating those variations. Human Tc1-like transposons are divided into Hsmar1 and Hsmar2 subfamilies. Although each types are inactive, one copy of Hsmar1 found in the SETMAR gene is underneath choice because ...
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